Granulation Technology
IMA granulation technologies: quality, efficiency and customisation across sectors.
IMA granulation technologies are designed to meet the needs of several market sectors, from pharmaceutical and nutraceutical to food and personal care, providing a broad range of solutions that contribute to the final product quality.
Further to ensuring quality, our granulation machines are also designed to maximise production efficiency, minimise maintenance requirements and ensure sustainable performance. IMA granulation technologies can be conceived when a customer requires a specific function or needs to process a special product. Our extensive experience in granulation technology will always be able to deliver an appropriate answer.
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Granulation
Pharma
Granulation is a key initial step in the OSD manufacturing process. IMA develops wet granulation equipment including high-shear mixer granulators, fluid bed equipment for granulation and drying, and single-pot granulators and dryers. Integrated granulation lines are particularly suited to large-volume and long production runs, combining a high-shear mixer granulator with a fluid bed dryer for efficient granulation and drying.
Our portfolio includes different technologies:
• Top-spray granulation, where a liquid binder is sprayed onto powder particles in a fluidised bed.
• Bottom-spray coating, typically used for small cores and controlled-release formulations.
• High-shear granulation with vacuum drying, using the contained single-pot ROTO CUBE technology.
With over 40 years of experience, IMA supports customers throughout process development, optimisation, scale-up and technology transfer, as well as engineering and project management. -
Granulation
Personal Care
Granulation in this sector is essential to reduce fines, improve solubility or enhance subsequent processing of microgranules. IMA granulation technologies make every process smooth and highly efficient. IMA supplies a complete range of granulation machines: from equipment for R&D purposes to industrial equipment high-shear mixing machines. Fluid bed processors and high-shear mixer granulators achieve optimal mixing and maximum product yield, while reducing maintenance to a minimum. Powder-to-lather shampoos, body and face cleansers, water-activated powder beauty masks, solid shower gel or toothpaste. IMA equipment treats every product with care, preserving the functional properties of even the most fragile and heat-sensitive ingredients.
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Granulation
Food
IMA fluid bed granulators and high-shear mixer granulators allow for maximum product yield, while reducing maintenance and cleaning time to a minimum. Small laboratory-scale equipment for formulation and product development is available, while larger-scale industrial equipment covers all production volumes. Rapid mixer granulators are also part of a comprehensive product range. Pre-mixing is available for candies and chewing gums, instant soups, sauces, cake mixes, instant drinks, tea, coffee, as well as sugar decorations. Products are treated with care, preserving the nutritional properties of even the most fragile and heat-sensitive ingredients.
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Technology highlight
Quality
Through granulation, achieve outstanding tablet and capsule quality, leading to reproducible disintegration time and dissolution profile, meaning accurate dosage delivery.
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Technology highlight
Sustainability
Appropriate design measures that pay close attention to minimising footprint and height, as well as to requirements for main utilities so as to reduce energy and water consumption.
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Technology highlight
Safety
Design criteria used to create a safer working environment while maintaining equipment safety and process containment, preventing exposure to products and cross contamination as well as risk of explosion due to use of organic solvents and potentially explosive powders.
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Technology highlight
Flexibility
Modular design for fluid bed processor allows multipurpose use for various processes: granulation, pellet coating and API layering.
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Technology highlight
Costs
Design concept combined with modern services enable fast-track projects and address efficiency and production compliance, thereby reducing time-to-market and improving cost containment.
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Technology highlight
Efficiency
Smart product handling and transfer systems help to speed up production and increase throughput. Optimised ergonomics and smart WIP systems to reduce downtime.
5 min
Brands: IMA Active, IMA S.p.A. – Active Division, IMA S.p.A. – Automation Division Bologna
White paper
Effervescent tablet processing and packaging: why integrated lines are shaping the future.
6 min
Brands: IMA S.p.A. – Active Division, IMA Active
6 min
Brands: IMA Active, IMA S.p.A. – Active Division
White paper
ARCA: AI Root Cause Analysis.
8 min
Brands: IMA Active, IMA S.p.A. – Active Division
13 min
Brands: IMA S.p.A. – Active Division, IMA Active
7 min
Brands: IMA S.p.A. – Active Division, IMA Active
12 min
Brands: IMA S.p.A. – Active Division
White paper
The Energy Diary: powering sustainability.
6 min
Brands: IMA Active, IMA S.p.A. – Active Division
10 min
Brands: IMA Active, IMA S.p.A. – Active Division
15 min
Brands: IMA S.p.A. – Active Division, IMA Active
10 min
Brands: IMA S.p.A. – Active Division, IMA Active
11 min
Brands: IMA Active, IMA S.p.A. – Active Division
Case study
Algorithm: «Why we choose IMA».
3 min
Brands: IMA Active, IMA S.p.A. – Active Division
5 min
Brands: IMA Active, IMA S.p.A. – Active Division
7 min
Brands: IMA Active, IMA S.p.A. – Active Division
5 min
Brands: IMA Active, IMA S.p.A. – Active Division
5 min
Brands: IMA Active, IMA S.p.A. – Active Division
Case study
ARIA fluid bed granulator and MicroNIR
8 min
Brands: IMA Active, IMA S.p.A. – Active Division
5 min
Brands: IMA Active, IMA S.p.A. – Active Division
