Granulation for Pharmaceutical

Technology

Beyond granulation processes, delivering excellence

Wet granulation has always had a significant impact on batch production of OSD forms. It provides a major contribution to solving or mitigating issues related to the characteristics of the raw materials and ensuring reliable and higher quality end products. The combination of a high shear granulator with a fluid bed dryer is the most widely popular granulation technology, due to high versatility and productivity, especially in the case of large product volumes and long production campaigns. However, there is a variety of granulation technologies available to better address efficiency in manufacturing and to speed up time to market. More than 40 years of experience in wet granulation at IMA Active have been spent meeting the challenge of making granulation a science and no longer an art handled by a few experts with extensive practical experience. IMA Active provides competence for support at many levels: process control, optimisation and development, scale-up and technology transfer, engineering and project management, thus becoming the ideal partner for the whole project.

IMA Active offers all wet granulation technologies in an innovative key, suited to modern manufacturing needs.

Efficient, no-risk, lean operations with reduced costs and a close eye on safety and sustainability.

  1. Technology highlight


    Quality

    Through granulation, achieve outstanding tablet and capsule quality, leading to reproducible disintegration time and dissolution profile, meaning accurate dosage delivery.

  2. Technology highlight


    Sustainability

    Appropriate design measures that pay close attention to minimising footprint and height, as well as to requirements for main utilities so as to reduce energy and water consumption.

  3. Technology highlight


    Safety

    Design criteria used to create a safer working environment while maintaining equipment safety and process containment, preventing exposure to products and cross contamination as well as risk of explosion due to use of organic solvents and potentially explosive powders.

  4. Technology highlight


    Flexibility

    Modular design for fluid bed processor allows multipurpose use for various processes: granulation, pellet coating and API layering.

  5. Technology highlight


    Costs

    Design concept combined with modern services enable fast-track projects and address efficiency and production compliance, thereby reducing time-to-market and improving cost containment.

  6. Technology highlight


    Efficiency

    Smart product handling and transfer systems help to speed up production and increase throughput. Optimised ergonomics and smart WIP systems to reduce downtime.

Pharmaceutical Granulation

Pharmaceutical Granulation

Pharmaceutical Granulation

Machine overview

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