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The MINIMAX series provides scalable lyophilization technologies from formulation to full commercial production. Process analytical technologies (PAT) also help manufacturers to find desirable conditions and parameters for perfect drying outcomes. Pilot-scale freeze-drying is the optimal solution for scale-up operation volumes prior to industrial-scale production or even for small production batches. The aim is to achieve drug commercialisation objectives and bring parenteral products safely and quickly to market by enhancing product and process knowledge. This ensures superior product quality and uniformity and creates a data-rich environment ensuring successful operation of all freeze-drying system sizes.
MINIMAX benefits from all-round performance, a high level of redundancy and various configurable options making it a reliable and versatile solution for each application. MINIMAX can be integrated with isolation technology and automatic vial-loading systems. The unit can be pre-arranged to support the processing of non-aqueous solvents and high-potent products.
Production plant
IMA Life
Available in six configurations with shelf areas from 1.0 up to 3.9 m2.
CIP/SIP included.
Ice condenser capacity ranging from 29 to 78 kg with minimum condenser temperatures of -75°C.
Slot door suitable for RABS/isolator integration.
Compact and modular configuration to fit available room space.
Preventive maintenance software “Health monitoring” to reduce downtimes and cut costs.
Pre-arranged for the installation of PAT tools such as KRYOSEQ®controlled nucleation and QUANTUM mass spectrometer.
MINIMAX shelves are designed and manufactured with IMA Life’s patented FUSION™ technology, to ensure higher quality and enhance process reliability. The FUSION™ – FUSION PLUS shelves are lighter and more resistant than conventional solutions and offer enhanced heat transfer
properties.
| Model | Number of shelves | Vial pack area Manual loading (m2) | Vial pack (wxd) Manual loading (mm) | Vial pack area Auto loading (m2) | Vial pack (wxd) Auto loading (mm) | Condenser capacity (kg @12.7 mm ice) | Compressor configuration | LN2 configuration | Kryoair configuration |
| MINIMAX 1.0 | 3 | 1.1 | 615 x 615 | 1 | 615 x 536 | 32 | 2 x 5Hp Bitzer | LF25/12 | 1 x 23T-0 |
| MINIMAX 1.4 | 4 | 1.5 | 615 x 615 | 1.3 | 615 x 536 | 32 | 2 x 5Hp Bitzer | LF25/12 | 1 x 23T-0 |
| MINIMAX 2.0 | 4 | 2.3 | 615 x 930 | 2.1 | 615 x 837 | 58 | 2 x 5Hp Bitzer | LF25/12 | 1 x 23T-0 |
| MINIMAX 2.8 | 5 | 2.9 | 615 x 930 | 2.6 | 615 x 837 | 58 | 2 x 5Hp Bitzer | LF25/12 | 1 x 23T-0 |
| MINIMAX 3.3 | 6 | 3.4 | 615 x 930 | 3.1 | 615 x 837 | 75 | 2 x 8Hp Bitzer | LF25/12 | 1 x 23T-0 |
| MINIMAX 3.9 | 7 | 4 | 615 x 930 | 3.6 | 615 x 837 | 75 | 2 x 8Hp Bitzer | LF25/12 | 1 x 23T-0 |
| Minimum shelf temperature (5cst/1/6cst oil) | -55C/-60C | -65C | -60C | ||||||
| Minimum condenser temperature | -75C | -100C | -75C | ||||||
