Continuous Direct Compression: from theory to practice

The webinar focuses on evaluating the transition from batch to Continuous Direct Compression in pharmaceuticals, highlighting the advantages of continuous processes such as increased efficiency and reduced costs. Additionally, it compares the lubricant sensitivity of different excipients used in blending technologies, utilizing a tumbler blender for batch and an axial blender for continuous processes. Critical process parameters (CPPs) and excipient quality attributes are examined showing that optimizing these parameters improves product quality and facilitates a smoother transition to continuous manufacturing while maintaining critical quality attributes.