Quantum Freeze-Drying
Machine overview
Detect, quantify, monitor
QUANTUM smart Mass Spectrometer is a non-invasive technique capable of performing real-time, process-relevant, quantitative measurements. A multipurpose device for use in pharmaceutical freeze dryers, it detects contaminants and process gases at concentrations down to ppm levels. Not only does this allow for silicone oil detection and for non-aqueous solvent detection, but QUANTUM can also be used as a system leak detection tool and as a process analytical tool for scale-up and development studies.
Production plant
IMA Life
Machine highlights
-
Control panel
The Graphical User Interface (GUI) offers advanced features to support routine operation, while empowering skilled users to add customised capabilities.
-
Freeze-dryer integration
Easy integration with new or existing freeze dryers, both pilot and production scale.
-
Silicone oil detection
QUANTUM samples freeze dryer chamber air to detect vaporised silicone oil.
-
Helium leak detection
When helium is introduced at the leak source, QUANTUM enables detection of the leak.
-
Drying detection
Primary and secondary drying chamber moisture monitoring.
Easy Sw and interface
QUANTUM system is ready for Ethernet port communications and easy-to-use software and user interface.
Machine details
Technical information
| TECHNICAL DATA QUANTUM | |
| Measurement specification | Conditions/units |
| Installation | Complete in 2 working days |
| Mass range | 1-200 amu |
| Resolution | Better than 10% valley between peaks of equal height throughout the mass range |
| Communication interfaces | Ethernet |
| Mass number stability | Better than +/- 0.1amu over 8hrs |
Minimum detectable partial pressure | <2e-11 Torr |
Minimum detectable concentration | <100ppb for all common gases except <10ppm for H2 (trace gas detection limit) |
Maximum operational pressure | 500 mTorr |
Weight | 20 kg |
Ambient temperature | 10°C to 40°C |
| Power consumption | 88-264 VAC, 47/63 Hz, 600 Watts |
| Pneumatics | 60-80 psig CDA |