Lyofast Mini Series Freeze-Drying

Machine overview

The new lyo generation

Lyofast Mini range of freeze dryers responds to the growing demand for small-batch production of high-value products or personalized medicines. It offers a reliable, GMP-compliant compact freeze dryer that meets the highest standards of quality and sterility.
Freeze drying of the initial scale up batches provides an opportunity to test the robustness of the process, to understand the future technology requirements for industrial production, and to optimize the process, thus reducing the energy requirement and downstream production costs, adding commercial value to your product.
To cope with market drivers, Lyofast Mini series of freeze dryers have been developed to be suitable for the following applications: small batch production, clinical trials, product development and process cycle optimization, up scaling of the process for later use in production plants.

Production plant

IMA Life

Machine highlights


  1. Configurations

    Four different configurations available, from 1 to 2.8 m2


  2. CIP/SIP

    Automatic CIP-SIP included.


  3. Slot door

    Slot door suitable for RABS/isolator integration.


  4. Applications

    Suitable for applications with high-potent products and non-aqueous solvents.


  5. Temperature probes

    Redundant shelf inlet temperature probes and pressure sensors.


  6. SCADA system

    Lyomaster compact Scada and state-of-the-art control system featuring high redundancy to ensure optimal process control and enhanced final product quality.


  7. Induced nucleation

    Ready to be integrated with KRYOSEQ® for nucleation control.

Easy integration

Lyofast Mini can be easily integrated with UAF, RABS, isolators, automatic and semi-automatic loading and unloading systems.

IMA Life’s FUSION™ – FUSION PLUS™ shelves

LYOFAST MINI shelves are designed and manufactured in-house with IMA Life’s patented FUSION™ technology, to ensure higher quality and enhance process reliability. The FUSION™ – FUSION PLUS™ shelves are lighter and more resistant than conventional solutions and offer enhanced heat transfer properties.

General side view

Internal front view

Shelf stack internal details

Shelf stack overview

Shelf stack detail

Technical information

LYOFAST MINI TECHNICAL DATA
ModelNumber of shelves up toVial pack  area up to
Manual loading
(m2)
Vial pack (wxd)
Manual loading
(mm)
Vial pack area up to
Auto loading
(m2)
Vial pack (wxd)
Auto loading
(mm)
Condenser capacity (kg @12.7 mm ice)Compressor config.LN2 config.KryoAir config.
LYOFAST MINI 131.1615 x 6151613 x 536282 x 5Hp BitzerLF25/121 x 23T-0
LYOFAST MINI 1.54/31.5/1.1615 x 6151.3/1613 x 536282 x 5Hp BitzerLF25/121 x 23T-0
LYOFAST MINI 2.242.3615 x 9302.1613 x 837582 x 8Hp BitzerLF25/121 x 23T-0
LYOFAST MINI 2.85/42.9/2.3615 x 9302.6/2.1613 x 837582 x 8Hp BitzerLF25/121 x 23T-0
Minimum shelf temperature (5cst/1/6cst oil)-55C/-60C-65C-60C
Minimum condenser temperature-75C-100C-75C

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