Lyofast Mini Series Freeze-Drying
Machine overview
The new lyo generation
Lyofast Mini range of freeze dryers responds to the growing demand for small-batch production of high-value products or personalized medicines. It offers a reliable, GMP-compliant compact freeze dryer that meets the highest standards of quality and sterility.
Freeze drying of the initial scale up batches provides an opportunity to test the robustness of the process, to understand the future technology requirements for industrial production, and to optimize the process, thus reducing the energy requirement and downstream production costs, adding commercial value to your product.
To cope with market drivers, Lyofast Mini series of freeze dryers have been developed to be suitable for the following applications: small batch production, clinical trials, product development and process cycle optimization, up scaling of the process for later use in production plants.
Production plant
IMA Life
Machine highlights
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Configurations
Four different configurations available, from 1 to 2.8 m2.
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CIP/SIP
Automatic CIP-SIP included.
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Slot door
Slot door suitable for RABS/isolator integration.
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Applications
Suitable for applications with high-potent products and non-aqueous solvents.
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Temperature probes
Redundant shelf inlet temperature probes and pressure sensors.
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SCADA system
Lyomaster compact Scada and state-of-the-art control system featuring high redundancy to ensure optimal process control and enhanced final product quality.
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Induced nucleation
Ready to be integrated with KRYOSEQ® for nucleation control.
Easy integration
Lyofast Mini can be easily integrated with UAF, RABS, isolators, automatic and semi-automatic loading and unloading systems.
IMA Life’s FUSION™ – FUSION PLUS™ shelves
LYOFAST MINI shelves are designed and manufactured in-house with IMA Life’s patented FUSION™ technology, to ensure higher quality and enhance process reliability. The FUSION™ – FUSION PLUS™ shelves are lighter and more resistant than conventional solutions and offer enhanced heat transfer properties.
Machine details
Technical information
| LYOFAST MINI TECHNICAL DATA | |||||||||
| Model | Number of shelves up to | Vial pack area up to Manual loading (m2) | Vial pack (wxd) Manual loading (mm) | Vial pack area up to Auto loading (m2) | Vial pack (wxd) Auto loading (mm) | Condenser capacity (kg @12.7 mm ice) | Compressor config. | LN2 config. | KryoAir config. |
| LYOFAST MINI 1 | 3 | 1.1 | 615 x 615 | 1 | 613 x 536 | 28 | 2 x 5Hp Bitzer | LF25/12 | 1 x 23T-0 |
| LYOFAST MINI 1.5 | 4/3 | 1.5/1.1 | 615 x 615 | 1.3/1 | 613 x 536 | 28 | 2 x 5Hp Bitzer | LF25/12 | 1 x 23T-0 |
| LYOFAST MINI 2.2 | 4 | 2.3 | 615 x 930 | 2.1 | 613 x 837 | 58 | 2 x 8Hp Bitzer | LF25/12 | 1 x 23T-0 |
| LYOFAST MINI 2.8 | 5/4 | 2.9/2.3 | 615 x 930 | 2.6/2.1 | 613 x 837 | 58 | 2 x 8Hp Bitzer | LF25/12 | 1 x 23T-0 |
| Minimum shelf temperature (5cst/1/6cst oil) | -55C/-60C | -65C | -60C | ||||||
| Minimum condenser temperature | -75C | -100C | -75C | ||||||








