IMA for Pharmaceutical
Aseptic Powder Vial Processing Line
Integrated lines incorporating aseptic powder processing capabilities ensure maximum production efficiency as well as safety and accuracy.
High-speed Aseptic Powder Vial Processing Lines
The vacuum/pressure systems are characterised by a high dosing speed, up to 400 bottles per minute. They enable the use of up to three dosing stations for products in split-fill mode or to increase production capacity. 100% In-Process Control (IPC) is integrated into all configurations and ensures continuous monitoring and compliance with weight targets. These systems are designed for integration in aseptic environments thanks to technological assets including “SMART PLATES”, supported by motorised carts and with Unidirectional Air Flow (UAF). Vacuum/pressure systems can be combined with barrier solutions, such as open RABS or closed RABS. Combined configurations are possible, e.g. open RABS for feeding and capping and closed RABS for filling. For closed RABS or isolator setups, temperature and humidity can be controlled in the dosing area and toxic risk management is ensured in cases where high containment is required.
Auger screw systems allow a high dosing speed to be reached of up to 300 bottles per minute and support up to two dosing units, each equipped with three augers, for in-line processing of split-fill products or to increase production capacity. They are designed to maximise dosing accuracy and minimise product losses at batch end, ensuring high efficiency. They include cleaning-in-place (CIP) and sterilisation-in-place (SIP) capabilities of the dosing circuit, improving sterility assurance and reducing cross-contamination and downtime. Auger screw systems can be combined with open RABS, closed RABS and isolators, allowing for temperature and humidity control in the dosing area and managing high containment configurations.
Benefits
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Aseptic powder dispensing solutions stand out for their advanced technological edge that makes them market leaders, ensuring precision, speed and adaptability to the needs of modern pharmaceutical production. Vacuum/pressure systems offer ultra-high speed dosing, with flexible configurations that allow product split-filling or production increases thanks to three dosing stations.
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Technologies such as SMART PLATE and motorised UAF carts guarantee aseptic and fast management of the machine setup by ensuring that pre-sterilised dosing units can be conveyed and positioned. The ability to contain and precisely control temperature and humidity makes these systems ideally suitable for large-scale production.
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Additionally, these systems support automatic loading of bins or sterybags via automatic elevators, making them ideal for large-scale production and to process powdered antibiotics in particular.
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Auger systems combine speed with outstanding dosing accuracy. Ideal for potent products and microspheres, they minimise product losses and streamline management thanks to integrated CIP and SIP. Powder containers are safely managed with Powder Loading Isolators (PLI), further improving efficiency. The versatility of the configurations makes them suitable for any production scale. With features such as scalability, high containment and an approach focused on the quality and efficiency of the global aseptic process, these technologies are state-of-the-art in the market and the ideal solution for dispensing potent and non-potent aseptic powders.
